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2015 Dec;21(12):283947

Initially identified as nine fundamental biological drivers of aging (13), the list has been updated to include twelve hallmarks: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis (14)

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The signal peptide GHK works in combination with Cu (copper) in the skin and controls the anti-aging factors

Retrieved 21 January 2023