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The IGF-1/IGF-1R system has been shown to be an important promoter of tumor growth in various cancers, promoting tumor progression and metastasis by regulating multiple signaling pathways, such as those of PI3K/AKT and MAPK/ERK signaling (78,94)

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Common research focuses include its influence on: Storage & Handling: Keep lyophilized peptide at -20C for long-term stability

Part of the reason is that anti-TNF agents block one specific cytokine while leaving the rest of the inflammatory network intact