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10.1126/sciadv.adi1782 Summary Keywords acute myeloid leukemia, drug resistance, epigenetic dysregulation, combination strategies, relapse Citation Tang J, Ye X, Xu Z, Min T, Tian Z, Ma L, He Y and Jiang B (2025) Epigenetic mechanisms of drug resistance in acute myeloid leukemia: advances in small-molecule targeted therapy
O., Tomilin, N., Barbacid, M., Shupliakov, O

Consequently, treatment strategies remain primarily within the preclinical and clinical trial phases [137]

Subcutaneous administration (abdomen, thigh, deltoid) produces identical tissue concentrations at distant injury sites because the peptide travels through bloodstream and accumulates in areas undergoing active repair via concentration-gradient mechanisms
Mg2+ deficiency and cardiovascular diseases Low serum Mg2+ levels have been associated with increased cardiovascular mortality by causing cardiovascular problems and exacerbating pre-existing ones [3, 5,8, 43, 75, 93, 120, 167169]
