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Mice were initially group housed (three/cage) and allowed to acclimate to the colony environment maintained at a constant temperature (2123C) and humidity (4050%) on a 12-hour light-dark cycle (lights on 06001800 h)

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The low molecular weight and amphiphilic nature of ALA/DHLA enable antioxidant interactions across cell membranes and cytoplasmic compartments, enhancing intracellular antioxidant defense