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A summary of the studies conducted on cobalamin and its role in MS is given in Table 1

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Its anabolic and growth-promoting effects are largely indirect, primarily via stimulation of hepatic IGF-1 production, whilst its direct metabolic effects, particularly those related to lipid metabolism and adipose tissue regulation, are believed to be mediated by specific domains within the GH molecule itself

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For example, some MIC B12 (Methionine, Inositol, Choline + B12) blends are more sensitive to temperature and should be refrigerated both before and after first use