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Gilliland, R

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Source: Biosynthetic preparation

While InsR-A homodimer binds both insulin and IGF2 with high affinity, InsR-B homodimer and InsR-A/B heterodimer preferentially bind insulin but not IGF

The mice were anesthetized with an intraperitoneal injection of 1% sodium pentobarbital (60 mg/kg) and were euthanized by cervical dislocation
