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Among these targets, 71 were associated with A, Tau, A, and Tau (Figure 11A), specifically, PIK3CD, CDC42, PDE4D, HTR4, ADRA1B, ARG1, PTGS1, PRF1, ADRA2A, CD81, CRYAB, BACE1, CDK2, MDM2, ALDH2, CYP19A1, NOS2, CSNK1D, PRKACA, CSNK2A1, PLCG1, CBS, and MIF were significantly associated with A pathology, EPHB2, LCK, JUN, ZAP70, DPP4, HTR2B, MAPK10, HTR1A, VEGFA, HTR1B, CFTR, CHRM2, GBA2, GSTP1, MMP3, HTR3A, CD4, VDR, MAPK3, and CHEK2 were significantly associated with Tau pathology