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Treating brain ifosfamide-induced encephalopathy
& Dice, J
Perimenopause represents a phase of profound endocrine remodeling, during which rapid and irregular fluctuations in sex hormones, particularly E2 and progesterone, markedly impact brain regions, such as the hippocampus and prefrontal cortex, involved in mood regulation (48)
The selenium-thyroid-testosterone connection becomes particularly important for ageing men, as this mineral supports hormone production whilst combating age-related oxidative stress
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