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Consequently, this nanoplatform leverages multi-component synergy with precisely controlled release, orchestrating dual metabolic reprogramming across tumor cells and the immune landscape, thereby proposing a novel immunometabolic paradigm for lipid balance modulation in the TME

SELECTED REFERENCES Shay KP, et al

Direct GPX4 activity targeting has the potential to trigger ferroptosis in cells [27]

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Lastly, the models were trained and tested on American and Caucasian-skewed cohorts, and future studies should assess the generalizability of the findings in more ethnically and geographically diverse populations