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53, The Waldstein

Alpha-Lipoic Acid Attenuates Silica-Induced Pulmonary Fibrosis by Improving Mitochondrial Function via AMPK/PGC1 Pathway Activation in C57BL/6J Mice

J Assist Reprod Genet (2016) 33(5):62735

Among 79 CYP2D6/CYP2C19antidepressant pairs with established CPIC evidence levels (A, A/B, or B), approximately 48% of ADR-associated pairs and 21% of ineffectiveness-associated pairs were actionable, signifying that genotype-guided interventions could potentially mitigate nearly half of ADR cases and one-fifth of therapeutic failures

doi: 10.1038/nature08268 196 McCarthyAMKumarNPHeWReganSWelchMMoyBet al