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Similarly, in azoxymethane-induced colon carcinogenesis in Balb/C mice, luteolin reduced MMP-9 and MMP-2 levels, suppressed tumor progression, and elevated TIMP-2 expression, demonstrating antimetastatic and chemopreventive effects at a 1.2 mg/kg daily oral dose [133]

Mehta, A

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Guiu, J

Sanghi A, Gruber JJ, Metwally A, Jiang L, Reynolds W, Sunwoo J, et al
