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2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society
Raquel D
In ALS, mutations lead to misfolding or aberrant conformational changes via oxidation leading to toxic gain of function and anomalous protein aggregation [16].The aggregates, in turn, lead to oxidative stress and mitochondrial dysfunction [17]
[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Pieren D
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