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Recently, solid evidence proved that hypoxia microenvironment is a typical characteristic of CSC-enriched microenvironment, which could induce the higher expression of ALDH and upregulate the CSC-enriched microenvironment

This disruption not only impairs nutrient absorption but also creates an environment conducive to bacterial overgrowth

Reduces pigmentation caused by the sun's UV radiation

Science Transl Med 7:299rv4299rv4

The increase in CP expression was verified in the GSE49036 and GSE20164 datasets (Table 3)
