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Enzymatic antioxidants such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) play crucial roles in detoxifying ROS and maintaining redox balance within melanocytes 46

In aged non-human primates and elderly humans, studies show that Epithalon or epithalamin administration restored nocturnal melatonin secretion, suggesting a rejuvenation of the pineal endocrine function [4]

This holistic approach aligns well with the complexity of the central nervous systems redox balance, offering hope that sustained lifestyle modifications will yield meaningful neuroprotective benefits and enhance quality of life, even as populations worldwide face the cognitive challenges of longer lifespans

Castellv P, Lucas-Romero E, Miranda-Mendizbal A, Pars-Badell O, Almenara J, Alonso I, Blasco M, Cebri A, Gabilondo A, Gili M (2017) Longitudinal association between self-injurious thoughts and behaviors and suicidal behavior in adolescents and young adults: a systematic review with meta-analysis