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doi: 10.1186/s13048-021-00849-2 15 Sharifi-RadJQuispeCCastilloCMSCarocaRLazo-VlezMAAntonyakHet al

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Until it is convincingly demonstrated that without chronic ROS production, MASLD/MASH progression is markedly delayed, a conclusion that hepatic ROS production (associated with greater levels of lipid metabolism) is a major contributor to disease pathogenesis cannot be conclusively made