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Description
Luo W, Kinsey M, Schiffman JD, Lessnick SL
Gastrointestinal problems
The tyrosine addition to AOD-9604 does a few things: Better stability The tyrosine at the N-terminus makes the molecule more resistant to enzymatic degradation, extending its functional half-life
Recently, this challenge has been overcome by the dynamic copy number regulation system, which works by regulating key genes of the plasmid replication machinery (priming RNA (RNA-p) and inhibitory RNA (RNA-i))
[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Zhang CS, Hawley SA, Zong Y, Li M, Wang Z, Gray A, Ma T, Cui J, Feng JW, Zhu M, et al
