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Opioid painkillers should be avoided, as Suboxone blocks their effects and can trigger withdrawal symptoms

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There is also a form packaged in prefilled syringes for convenience in some settings (e.g

Similar to IL-31, OSM induces delayed itching in mice and enhances histamine-induced pruritus by enhancing the excitability and sensitivity of the sensory neurons to pruritogens instead of directly activating them

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