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Previous studies showed that unsaturated lipid peroxidation-derived aldehydes such as 4-HNE triggered autophagy in a JNK-dependent manner by activating the endoplasmic reticulum stress (ER) response

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Also, the insulin/insulin growth factor-1 signaling pathway is involved in the anti- Plasmodium response of mosquitoes (Pakpour et al., 2014), and RNA interference pathways (RNAi), which are discussed in greater detail in section 5.5, are essential components of the antiviral response