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This mean value is qualitatively labeled between very hard and very very hard for the effort of the 5-km runs

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Under normal circumstances, O-GlcNAcylation functions as a sensor for nutrient availability and cellular stress, modulating the stability, distribution, and activity of many proteins within the nucleus and cytoplasm [91]

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The Nrf2 system activates the transcription of a number of antioxidant enzymes, including HO, NAD(P)H, quinone oxidoreductase 1, Prdx, and -glutamyl-cysteine synthetase, the latter a rate-limiting enzyme in the synthesis of glutathione