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Combined modality therapy of cT2N0M0 esophageal cancer: the University of Texas M
doi: 10.1016/0888-7543(95)80142-9
Subsequently, Yagoda and Yangs groups demonstrated that iron chelators could inhibit this type of cell death, discovered that Ras-selective lethal 3 (RSL3) mimicked Erastins effects in RAS-mutant cells, and found that elevated levels of ROS and iron were closely associated with RAS signaling (Yagoda et al., 2007
These senescent cells are thus irreparably damaged, but they do not die
