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Intriguingly, CD8 + T cells exhibit an adaptive response by upregulating an alternative glutamine transporter, SLC6A14, thereby sustaining both glutamine uptake and immune effector function within V9302-treated tumors [134]
Furthermore, the novel glutamine metabolism-related genes guidance strategies for predicting survival and chemo-immunotherapy efficacy may also apply to cancers other than bladder cancer [207]
Nale JY, Spencer J, Hargreaves KR, Buckley AM, Trzepinski P, Douce GR, Clokie MR
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Zhang N, Ji N, Jiang WM, Li ZY, Wang M, Wen JM, et al
