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Keep three levels of biology distinct: the parent hormone (full-length hGH, with broad endocrine effects), the lipolytic domain (the C-terminal region thought to carry the fat-mobilizing signal), and the engineered fragment (AOD-9604, a stabilized reproduction of that domain)

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[14] Small clinical trials indicate that maternal supplementation of 4,000 IU day or staggered 50,000 IU oral doses can safely maintain 25-hydroxyvitamin D above 30 ng mL without inducing hypercalcaemia, whereas single injections of 300,000 IU are reserved for severe malabsorption emergencies when benefits outweigh theoretical teratogenic risk