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Although folate deficiency and B12 deficiency can have similar symptoms, they are different vitamins and deficiencies must be treated differently

The animal study was reviewed and approved by Animal welfare and ethics committee from Peking Union Medical College Hospital

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Biomarkers for Disease Progression : Objective markers such as cerebrospinal fluid (CSF) levels of synuclein, neurofilament light chain (NfL), and dopamine transporter imaging (DATSPECT) should be used to monitor neurodegeneration and treatment response [122, 123, 124]

486 Clinically, early recognition and differentiation of focal and multifocal neuropathies are crucial for effective management, which includes stringent glycemic control, pain management, and addressing underlying vascular or inflammatory processes