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The loss of MT stabilization effect by tau compromises regulatory functions of cytoskeleton, axonal transport and eventually leading to neuronal malfunction, neurodegeneration and AD [173]

The gut microbiome system can be disrupted, leading to significant changes to the bacterial composition known as dysbiosis

Important Limitations and Warnings Honesty about AOD-9604's limitations serves users better than hype

10.1016/j.psychres.2015.05.021 133
Atrophic muscles were characterized by a significant increase in TNF-, NF-B, IL-6 levels [121,122] and in ROS production by dysfunctional mitochondria [123]
