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In a 2012 double-blind randomized controlled trial (N = 70 LOE2a), 500 mg of LC was administered daily to migraine patients for 12 weeks
On the other hand, decreased activity of HMG CoA reductase, the enzyme that controls the rate of de novo cholesterol synthesis by the cell, leads sequentially to a fall in cell cholesterol, increased expression of apo B/E (LDL) receptors, enhanced uptake of cholesterol from the circulation, and a reduction in the plasma cholesterol concentration
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Aliquots of stock solutions were complexed with fatty-acid-free BSA (10% solution in 150 mM NaCl
It is commonly included in studies on cardiometabolic health, renal function, and microbiome-diet interactions [4]
