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Because the peptide potently and aggressively stimulates angiogenesis via the VEGF/VEGFR2 pathways, there is a theoretical, but highly biologically plausible, risk that BPC-157 could inadvertently supply massive new blood flow to existing, undiagnosed malignant tumors, thereby acting as a catalyst for rapid cancer metastasis
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In Adipoq / mice, P5 treatment can achieve similar effects
Other antiviral polypeptides prevent viral infection via other processes, such as lectin-like human defensins-5 (HD5) which binds and shields the host angiotensin converting enzyme-2 (ACE2) receptor [21], P9 which inhibits the late endosomal acidification to prevent viral RNA release [22], and RTD-1 which activates host-protective immune responses [23]
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