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Biosci Biotechnol Biochem

The aggregation of copper-bound mitochondrial proteins triggers proteotoxic stress, leading to the destabilization and breakdown of Fe-S clusters

these functions are associated with high levels of CCL21, CXCL12, MIP1a, MIP2, KC, CXCL3 and TGF- in the whey extracts [47, 48]

[3] Subsequent structural optimization introduced the N-terminal tyrosine residue, yielding the compound now designated AOD-9604

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