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5.2 ROS-mediated mitochondrial dysfunction and vicious cycle formation 5.2.1 ROS-induced mitochondrial membrane damage and functional collapse Excessive mitochondrial ROS are central mediators of membrane disruption and bioenergetic failure

Ding B, Chen H, Wang C, et al

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Furthermore, elucidating the interplay between GSH and critical molecular pathways, including mitochondrial function and lipid metabolism, could provide valuable mechanistic insights and help identify more biomarkers predictive of treatment response

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