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Assuming a 1:1:1 group allocation ratio, a sample size of 29 teeth per group was required to achieve 80% power to detect between-group differences

What's happening in the gut

Toriumi, K., Miyashita, M., Suzuki, K., Yamasaki, N., Yasumura, M., Horiuchi, Y., Yoshikawa, A., Asakura, M., Usui, N., Itokawa, M., & Arai, M

van der Valk R, Webers CA, Schouten JS, Zeegers MP, Hendrikse F, Prins MH (2005) Intraocular pressurelowering effects of all commonly used glaucoma drugs: a meta-analysis of randomized clinical trials

Those with Celiac disease, Crohns, or other gut disorders, and those taking drugs to calm heartburn, like omeprazole, have difficulty absorbing B12