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58.4% male, 38.0% aged 60 years, 81.9% upper limb spasticity only

Both acute and chronic administration of IUB288 increase energy expenditure, as measured by indirect calorimetry, in chow-fed mice, and this effect is similarly reflected in an increase in core temperature in diabetic mice [14]

When dosed appropriately, TB500 side effects are generally described as mild and transient, but human safety data remain limited

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Some therapists report less pain and quicker return to function, likely due to reduced inflammation and enhanced matrix production