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Patients have also occasionally experienced thyroid tumors

The authors reported that intra-articular AOD-9604 injection in the rabbit osteoarthritis model produced macroscopic, histologic, and biomechanical evidence of cartilage preservation relative to untreated controls, with the combination of AOD-9604 plus hyaluronic acid yielding the most consistent chondroprotective effect [4]

B12 is involved in metabolism and energy production, so if a deficiency is contributing to low energy and making it hard to exercise, injections might indirectly support weight loss efforts by boosting energy