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In AD, EWAS studies utilising bulk brain tissue have identified multiple genes with DNA methylation changes associated with the disease and its pathological burden [47, 61, 98, 111], and meta-analyses have identified significant changes across multiple brain regions [91, 96, 99, 118]

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Nature 496 , 445455 (2013)

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HodgsonE.2004A textbook of modern toxicology, John Wiley & Sons, Inc., Retrieved from 52

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