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In addition, NRF2 is capable of increasing the expression of many autophagy-related genes that present a common ARE sequence in their promoters, including Sequestosome-1 ( SQSTM1 ) gene (encoding protein 62) [164], and of attenuating inflammation by blocking pro-inflammatory cytokine (IL-6 and IL-1) transcription [132], thus highlighting its crucial contribution to different cellular pathways

P2Y1, P2Y purinoreceptor 1

Monthly booster sessions assist in maintaining the results over time after your goal has been reached

10.1038/s41433-024-03103-3 15 GalloA

More is not always better with peptides, and some people experience irritation at higher concentrations