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But this depends on weight, age and other factors

Human Psychopharmacology: Clinical and Experimental, e2872.
TNFalpha drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling

In addition, painful sensations including non-evoked burning, shooting or electric shock-like pain as well as mechanical or thermal allodynia or hyperalgesia frequently occur (Postma et al., 1993
