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[61] Liu J, Killilea DW, Ames BN.Proc Natl Acad Sci U S A

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It has been proposed that NAD(P)H:quinone oxidoreductase 1 (NQO1) acts as a redox-sensitive switch to regulate the response of cells to changes in the redox environment (Ross and Siegel, 10 may result in fairly different plasma concentration-time profiles after CoQ 10 administration (Weis et al., 10 is eliminated via feces, with only a fraction of ingested CoQ 10 reaching the blood and ultimately the various tissues and organs (Bentinger et al., For these reasons, CoQ appears suitable for use in the treatment of different diseases

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