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ISSN 0164-4033
Genetic variants of alanine glyoxylate aminotransferase (AGXT), an enzyme involved in oxalate metabolism, have been correlated with the severity of oxaliplatin-induced CIPN (Gamelin et al., 2007)
More importantly, the reperfusion or restoration of blood flow after ischemia can also induce the increase of ROS and lipid peroxidation, leading to tissue neuronal damage and worsening of the inflammatory response
Blood 2010
These areas may drip with sweat, while the rest of the body stays dry
