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Whilst a handful of enterovirus vaccines are available, including for poliovirus (PV) and for EV-A71 (frequently responsible for serious outcomes of hand, foot and mouth disease) 1,2,3,4 , there are as yet no licenced anti-enterovirus drugs, despite evidence for efficacy in clinical trials and reports of extremely high potency for compounds targeting a pocket internal to capsid protein VP1 (termed here the P site) 5,6

Researchers study glutathione in the context of cellular redox balance and antioxidant systems

ACSL4 expression is also regulated by radiotherapy and immunotherapy (Mbaveng et al., 2018)

Jaspers JE, Kersbergen A, Boon U, Sol W, van Deemter L, Zander SA, et al

Baudrimont I, Ahouandjivo R, Creppy EE