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Among the different choices, black cumin has emerged as a viable candidate for health improvement due to its low toxicity and multiple modes of action

The initial LECs constitutively express CCL21 to actively recruit DCs via CCL21-CCR7 chemotaxis (105)

Under oxidative damage conditions, Nrf2 transports to the nucleus, then binds to the antioxidant response element (ARE), and enhances sequence to initiate transcription of cytoprotective genes NF-E2 related factor 2 (Nrf2) has been seen to get modulated in various neurodegenerative diseases