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Exposure to PS-NPs and PS-MPs promoted ferroptosis in cardiomyocytes and endothelial cells by upregulating pro-ferroptotic ACSL4 and downregulating antioxidant enzyme GPX4, leading to ROS accumulation, mitochondrial membrane depolarization, and reduced cell viability [19, 178, 179]

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Purity testing is essential : If a patient and their physician decide to explore BPC-157, independent third-party purity testing of the product is something I consider non-negotiable