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The most important methyl donor in humans is S-adenosylmethionine (SAM) , which we will take a closer look at below (1)
The current standard treatment for patients with breast cancer includes the combination of surgery, radiation, hormone therapy and chemotherapy drugs, such as anthracyclines, cyclophosphamide, taxanes and platinum compounds [2, 3]

Zhang B., Dai X., Bao Z., et al., Targeting the Subpocket in Xanthine Oxidase: Design, Synthesis, and Biological Evaluation of 2[4Alkoxy3(1HTetrazol1Yl) Phenyl]6Oxo1,6Dihydropyrimidine5Carboxylic Acid Derivatives, European Journal of Medicinal Chemistry 181 (2019): 111559, 10.1016/j.ejmech.2019.07.062

Aldigier JC, Kanjanbuch T, Ma LJ, Brown NJ, Fogo AB
