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There is a large gap waiting to be filled by subsequent researchers to yield better therapeutic targets and methods to cure breast cancer, and the role of GPxs in breast cancer should be studied as an extremely important issue

The GLC gene is induced also by exposure to reactive oxygen species and nitric oxide species [15]

doi: 10.1093/humrep/dew303 [DOI] [PubMed] [Google Scholar] 117

Due to the interference with DNMTs capacity to bind DNA, hydroxyl radicals (HO) also encourage global hypomethylation

Next, the cells were treated with a trypsin/EDTA solution (#T4049, Sigma-Aldrich, USA) for 10 minutes at 37C and then centrifuged at 1200 rpm