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Effects on neuronal potassium (K + ) channelsof which four major groups [voltage-gated K + channels (K V ), Ca 2+ -activated K + channels (K Ca ), two-pore K + channels (K 2P ) and inwardly-rectifying K + channels (K ir )] are expressed in peripheral nervesfurther exacerbate altered neuronal excitability in CIPN

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10.3390/antiox11010050 23 LangC

Thats understandable, but it misses the bigger issue