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Conversely, the increased export of 2-Oxoglutarate into the cytosol could augment the activity of Fe (II) 2-oxoglutarate (2OG)dependent oxygenases, enzymes that catalyze a variety of critical reactions including hydroxylation, halogenation, desaturation, and ring transformation

Similar content being viewed by others Introduction Disulfide bonds play a critical stabilizing role in many protein structures by forming cross-links between different regions of polypeptide chains
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The relationship between body mass and metabolic rate is not perfectly linear across species

These results strongly support that USP2 regulates ferroptosis under TGF-1 stimulation

doi: 10.1016/j.fct.2012.06.034
