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Description
Peroxiredoxin-2 and STAT3 form a redox relay for H 2 O 2 signaling
Iron overload is a defining feature of ferroptosis, which promotes lipid ROS accumulation by producing hydroxyl and alkoxyl radicals through the Fenton reaction 13
Cutting back on these exposure hotspots helps our glutathione chill out a bit
In summary, it can be postulated that during Fe deficiency the accumulation of GSH in cells can activate the vacuolar Fe exporters like AtNRAMP3 and AtNRAMP4 to facilitate Fe export from the vacuolar reserve
doi: 10.1161/ATVBAHA.124.321201
