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The GSSG that results from this process must then diffuse to more superficial layers of the lens where it can be reduced to regenerate GSH ( Fig

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Swimmers should also avoid digging or stirring up sediment at the bottom of lakes, ponds and rivers as this is where amebae are most likely to live

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These observations indicate that alterations in amino acid metabolism may contribute to the broader metabolic milieu induced by KD, although their precise impact appears to vary across experimental and clinical settings