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Description
The aberrant activation of Nrf2 in cancer cells leads to increased expression of Glucose-6-phosphate dehydrogenase (G6PD), transketolase (TKT), 6-phosphogluconate dehydrogenase (PGD), and other metabolic enzymes promoting glutamine and glucose metabolism in pentose phosphate pathway (PPP) and increasing synthesis of amino acids participating in metabolic reprogramming required for cell proliferation (Mitsuishi et al
Reduced glutathione (GSH) yields several systemic effects, including improvements of liver abnormalities and diabetic complications, protection from viral infections, and antitumor activities [3]

Influence of n-acetylcysteine maintenance on the pharmacodynamic effects of oral ethanol

Arefhosseini, S

Redox Biol 29:101378
