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In a further aspect of the invention, one or more chemical entities (e.g., nicotinamide riboside, nicotinamide mononucleotide) that increase intracellular NAD+ levels to provide muscular therapy is contacted with a cell expressing NNMT followed by contacting said cell expressing NNMT one or more NNMT inhibitors (such as a cation of Formula I or IA, or otherwise disclosed herein)

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It must be determined that it meets at least two of the following three criteria: It has the potential to enhance or enhances sport performance It represents an actual or potential health risk to the athletes It violates the spirit of sport WADA also published: the 2024 Summary of Major Modifications and Explanatory Notes as compared to the 2023 List

Initial consultation: $200-400 Monthly therapy costs: $400-800 depending on peptides Follow-up appointments: $100-200 each Lab work: Often additional, $200-500 Traditional clinics work best for people who value face-to-face interaction with physicians, need complex multi-peptide protocols, or have health conditions requiring close monitoring

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