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2.11 Cytokine quantification For the pro-inflammatory cytokines (IL-8, IL-6 and TNF), apical samples were centrifuged at 900 g for 5 min to remove debris

Shi C, Wang M

Hence, the low levels of thiomethyl metabolites observed after APAP exposure are probably associated to the limited cytochrome P450 capabilities of in vitro models to generate NAPQI metabolites via CYP2E compared to in vivo hepatocytes

The condition may cause discomfort and itchiness, significantly impacting the individuals quality of life if untreated

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