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Sakaguchi M, Okagawa S, Okubo Y, Otsuka Y, Fukuda K, Igata M, et al

Metformin combined with glycolysis inhibitor Metformin exerts toxic effects on NSCLC cells as an OXPHOS inhibitor (90)

Smoking also contributes to skin ageing and may lead to early signs of ageing, such as wrinkles, fine lines, and discoloration

Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice

Each approach has genuine trade-offs
