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This paper shows the involvement of MSH6 in LS

Front Immunol 13:934494 Zhao C et al (2025) Immunoadjuvant-functionalized metal-organic frameworks: synthesis and applications in tumor immune modulation

Modern studies indicate that licorice can inhibit the intestinal absorption of diester diterpene alkaloids from Aconitum species and promote their metabolism and excretion through the induction or regulation of drug-metabolizing enzymes and efflux transporters, thereby mitigating toxicity [39]

In contrast, RNA interference employs small double-stranded RNA molecules, such as siRNA, which integrate into the RNA-induced silencing complex (RISC)

(Pennsylvania, PA: IGI Global)